MediaScout® products from Atoll GmbH, Germany, provide a range of tools for Resin Screening, Methods Scouting and High Throughput or Parallel Chromatography. Process Development scientists working to develop chromatographic steps for Downstream Bioprocesses should ensure they are selecting the most suitable resin/media for any particular step operation.

MiniColumn®96

well format chromatography columns can be configured to

• screen up to 96 totally different resins in parallel
• evaluation of different loading or elution conditions with different resins of the same chemistry
• explore both resin types and load or elution conditions at the same time
• available as 50, 100 or 200 microlitre packed volume minicolumns
• for use with gravity flow, centrifugally assisted flow or pipette operation

MediaScout RoboColumn®

are designed specifically for use with fluid handling robotic systems

• automate the resin screening process
• run up to 96 columns in parallel for analysis or small scale preparative work
• available as 50, 100 or 200 microlitre packed volume minicolumns

MediaScout MiniChrom®

columns use the same basic design to provide individual columns for detailed methods evaluation which connect to any chromatography methods development workstation or HPLC

• evaluate and optimise the separation conditions
• prepare purified material for research use
• all materials available in the same format column
• all materials packed to high performance under optimised conditions
• available as 50, 100, 200, 500 microlitre, 1.0ml and 5ml standard column volumes

MediaScout ValiChrom®

validation columns are purpose designed to provide similar quality packed bed to your process column for scale down validation studies

• packed with optimised or specified compression to any bed height (mm) between 5cm and 60cm
• with your own resin (specific lot number) fresh or used resin if required
• fixed, predetermined bed height column, no adjustable bed height inaccuracies
• precision bore glass columns with full bed visibility, for visual confirmation of packing integrity
• 1cm square cross-sectional area, volumetric flow rate (ml/hr) equals linear flow rate (cm/hr)
• straightforward calculation of scale up dynamic capacity data
• virus or endotoxin clearance studies, cleaning validation and many other applications
• efficiency, asymmetry and pressure/flow data available on request

MediaScout ResiQuot®

resin sampling device, designed to dispense resin aliquots into 96 well format with accuracy

• avoid the inaccuracy of pipettes when used to dispense slurries
• perform isotherm studies in parallel
• your own resin, even your own Lot number may be packed by Atoll
• determine equilibrium capacity for many resins at the same time or under different conditions

Atoll offers a unique purpose-designed platform for resin screening

Atoll brings true parallel chromatography within the reach of everyone